FAM111A anticorps

N° du produit ABIN8121366

L’anticorps anti-FAM111A Monoclonal Lapin est utilisé pour la détection de FAM111A dans des échantillons de Humain. Il a été validé pour IHC, WB, IF et ICC.

Aperçu rapide pour FAM111A anticorps (ABIN8121366)

Antigène: FAM111A (Family with Sequence Similarity 111, Member A (FAM111A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp FAM111A est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AB2252

Détail du produit anti-FAM111A anticorps

Fonction: FAM111A Rabbit mAb

Specificité: This antibody detects endogenous levels of FAM111A protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: Recombinant protein (or fragment).

Isotype: IgG

Information d'application

Indications d'application: WB, 1:1000-1:5000 | IHC, 1:100-1:300 | IF, 1:100-1:300 |

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur FAM111A

Antigène: FAM111A (Family with Sequence Similarity 111, Member A (FAM111A))

Autre désignation: FAM111A

Sujet:

Synonyms: FAM111A, KIAA1895, Serine protease FAM111A,

Background: The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA) . Reduced expression of this gene resulted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia) , both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],

Gene Name: FAM111A, KIAA1895

Protein Name: FAM111A

ID gène: 63901

UniProt: Q96PZ2