Fascin anticorps
Aperçu rapide pour Fascin anticorps (ABIN8121394)
Antigène
Voir toutes Fascin (FSCN1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Fascin Rabbit mAb
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Specificité
- This antibody detects endogenous levels of Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55) protein.
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Purification
- The antibody was purified by protein A affinity chromatography.
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Immunogène
- Recombinant protein (or fragment).
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Isotype
- IgG
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Indications d'application
- WB, 1:10000-1:20000 | IHC, 1:1000-1:5000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at-20°C. Avoid freeze / thaw cycles.
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- Fascin (FSCN1)
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Autre désignation
- Fascin
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Sujet
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Synonyms: Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)
Background: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]
Gene Name: FSCN1 FAN1 HSN SNL
Protein Name: Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)
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ID gène
- 6624
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UniProt
- Q16658
Antigène
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