FES anticorps (pTyr713)

N° du produit ABIN8121416

Cet anticorps Lapin Polyclonal détecte spécifiquement FES dans WB. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour FES anticorps (pTyr713) (ABIN8121416)

Antigène: FES (Feline Sarcoma Oncogene (FES))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FES est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FES anticorps

Épitope: pTyr713

Fonction: c-Fes (Phospho Tyr713) Antibody

Specificité: This antibody detects endogenous levels of c-Fes (Phospho-Tyr713) at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human c-Fes (Phospho-Tyr713)

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur FES

Antigène: FES (Feline Sarcoma Oncogene (FES))

Autre désignation: c-Fes

Sujet:

Synonyms: Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)

Background: This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009],

Gene Name: FES FPS

Protein Name: c-Fes (Phospho-Tyr713)

ID gène: 2242

UniProt: P07332

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Signaling Events mediated by VEGFR1 and VEGFR2