Fibrillarin anticorps

N° du produit ABIN8121431

Cet anticorps Lapin Monoclonal détecte spécifiquement Fibrillarin dans WB, IHC, IF, IP et ELISA. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Fibrillarin anticorps (ABIN8121431)

Antigène: Fibrillarin (FBL)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Fibrillarin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA

Clone: AB1766

Détail du produit anti-Fibrillarin anticorps

Fonction: Fibrillarin Rabbit mAb

Specificité: This antibody detects endogenous levels of Fibrillarin protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: Recombinant protein (or fragment).

Isotype: IgG

Information d'application

Indications d'application: WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur Fibrillarin

Antigène: Fibrillarin (FBL)

Autre désignation: Fibrillarin

Sujet:

Synonyms: rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (34 kDa nucleolar scleroderma antigen)

Background: This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008]

Gene Name: FBL FIB1 FLRN

Protein Name: Fibrillarin

ID gène: 2091

UniProt: P22087

Pathways: Ribonucleoside Biosynthetic Process