FKBP1A anticorps (AA 1-50)

N° du produit ABIN8121463

Cet anticorps anti-FKBP1A Polyclonal Lapin (ABIN8121463) détecte spécifiquement FKBP1A dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour FKBP1A anticorps (AA 1-50) (ABIN8121463)

Antigène: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP1A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-FKBP1A anticorps

Épitope: AA 1-50

Fonction: FKB1A Antibody

Specificité: FKB1A Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human protein AA range: 1-50

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur FKBP1A

Antigène: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Autre désignation: FKB1A

Sujet:

Background: The protein encoded byThis gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided b

Gene Name: FKBP1A FKBP1 FKBP12

Protein Name: Peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Calstabin-1) (FK506-binding protein 1A) (FKBP-1A) (Immunophilin FKBP12) (Rotamase)

ID gène: 2280

UniProt: P62942

Pathways: Negative Regulation of Transporter Activity, Methionine Biosynthetic Process