GEN1 anticorps (AA 61-111)

N° du produit ABIN8121631

Cet anticorps anti-GEN1 Polyclonal Lapin (ABIN8121631) détecte spécifiquement GEN1 dans WB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour GEN1 anticorps (AA 61-111) (ABIN8121631)

Antigène: GEN1 (Gen Endonuclease Homolog 1 (GEN1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GEN1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GEN1 anticorps

Épitope: AA 61-111

Fonction: GEN Antibody

Specificité: This antibody detects endogenous levels of GEN at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human GEN AA range: 61-111

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur GEN1

Antigène: GEN1 (Gen Endonuclease Homolog 1 (GEN1))

Autre désignation: GEN

Sujet:

Background: This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains.The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016],

Gene Name: GEN1

Protein Name: GEN

ID gène: 348654

UniProt: Q17RS7

Pathways: Réparation de l'ADN