GSTM2 anticorps

N° du produit ABIN8121720

L’anticorps anti-GSTM2 Polyclonal Lapin est utilisé pour la détection de GSTM2 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour GSTM2 anticorps (ABIN8121720)

Antigène: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GSTM2 anticorps

Fonction: GSTM2 Antibody

Specificité: GSTM2 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur GSTM2

Antigène: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Autre désignation: GSTM2

Sujet:

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. [provided by RefSeq, Jul 2008],

Gene Name: GSTM2 GST4

Protein Name: Glutathione S-transferase Mu 2 (EC 2.5.1.18) (GST class-mu 2) (GSTM2-2)

ID gène: 2946

UniProt: P28161

Pathways: Negative Regulation of Transporter Activity