CD42b anticorps (AA 500-627)

N° du produit ABIN8121768

L’anticorps anti-CD42b Monoclonal Souris est utilisé pour la détection de CD42b dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC, ELISA et IF.

Aperçu rapide pour CD42b anticorps (AA 500-627) (ABIN8121768)

Antigène: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD42b est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: AB2399

Détail du produit anti-CD42b anticorps

Épitope: AA 500-627

Fonction: CD42b mouse mAb

Specificité: This antibody detects endogenous levels of CD42b protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 500 - 627 of the human CD42b protein.

Isotype: IgG

Information d'application

Indications d'application: IHC, 1:200-1:1000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur CD42b

Antigène: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Autre désignation: CD42b

Sujet:

Synonyms: GP1BA, Platelet glycoprotein Ib alpha chain, GP-Ib alpha, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b-alpha, CD42b,

Background: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF) . The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is

Gene Name: GP1BA

Protein Name: CD42b

ID gène: 2811

UniProt: P07359