GP1BB anticorps (AA 90-150)

N° du produit ABIN8121769

Cet anticorps anti-GP1BB Polyclonal Lapin (ABIN8121769) détecte spécifiquement GP1BB dans IHC, IF et ELISA. L’anticorps est réactif avec des échantillons de Rat, Humain et Souris.

Aperçu rapide pour GP1BB anticorps (AA 90-150) (ABIN8121769)

Antigène: GP1BB (Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB))

Reactivité: Rat, Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GP1BB est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Détail du produit anti-GP1BB anticorps

Épitope: AA 90-150

Fonction: CD42c Antibody

Specificité: The antibody detects endogenous CD42c

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthetic peptide from human protein at AA range: 90-150

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur GP1BB

Antigène: GP1BB (Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB))

Autre désignation: CD42c

Sujet:

Synonyms: Platelet glycoprotein Ib beta chain (GP-Ib beta, GPIb-beta, GPIbB, Antigen CD42b-beta, CD antigen CD42c)

Background: Platelet glycoprotein Ib (GPIb) is a heterodimeric transmembrane protein consisting of a disulfide-linked 140 kD alpha chain and 22 kD beta chain. It is part of the GPIb-V-IX system that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion in the arterial circulation. GPIb alpha chain provides the VWF binding site, and GPIb beta contributes to surface expression of the receptor and participates in transmembrane signaling through phosphorylation of its intracellular domain. Mutations in the GPIb beta subunit have been associated with Bernard-Soulier syndrome, velocardiofacial syndrome and giant platelet disorder. The 206 amino acid precursor of GPIb beta is synthesized from a 1.0 kb mRNA expressed in plateletes and megakaryocytes. A 411 amino acid protein arising from a longer, unspliced transcript in endothelial cells has been described, however, t

Gene Name: GP1BB

Protein Name: Platelet glycoprotein Ib beta chain (GP-Ib beta) (GPIb-beta) (GPIbB) (Antigen CD42b-beta) (CD antigen CD42c)

ID gène: 2812

UniProt: P13224