HNF1A anticorps (pSer247)

N° du produit ABIN8122096

Cet anticorps anti-HNF1A Polyclonal Lapin (ABIN8122096) détecte spécifiquement HNF1A dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour HNF1A anticorps (pSer247) (ABIN8122096)

Antigène: HNF1A (HNF1 Homeobox A (HNF1A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNF1A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HNF1A anticorps

Épitope: pSer247

Fonction: HNF1α (Phospho Ser247) Antibody

Specificité: This antibody detects endogenous levels of Human HNF1α (phospho-Ser247)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized phosho peptide around human HNF1alpha (Ser247)

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur HNF1A

Antigène: HNF1A (HNF1 Homeobox A (HNF1A))

Autre désignation: HNF1alpha

Sujet:

Synonyms: Hepatocyte nuclear factor 1-alpha (HNF-1-alpha) (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1)

Background: The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],

Gene Name: HNF1A TCF1

Protein Name: HNF1α (Ser247)

ID gène: 6927

UniProt: P20823

Pathways: Hormone Transport, Carbohydrate Homeostasis