Integrin beta 7 anticorps (AA 671-720)

N° du produit ABIN8122265

Cet anticorps Lapin Polyclonal détecte spécifiquement Integrin beta 7 dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Integrin beta 7 anticorps (AA 671-720) (ABIN8122265)

Antigène: Integrin beta 7 (ITGB7)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Integrin beta 7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Integrin beta 7 anticorps

Épitope: AA 671-720

Fonction: Integrin β7 Antibody

Specificité: Integrin β7 Polyclonal Antibody detects endogenous levels of Integrin β7

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Integrin beta7. at AA range: 671-720

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Integrin beta 7

Antigène: Integrin beta 7 (ITGB7)

Autre désignation: Integrin beta7

Sujet:

Synonyms: Integrin beta-7 (Gut homing receptor beta subunit)

Background: This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013],

Gene Name: ITGB7

Protein Name: Integrin β7

ID gène: 3695

UniProt: P26010

Pathways: Integrin Complex