KPNA6 anticorps (AA 404-454)

N° du produit ABIN8122417

Cet anticorps anti-KPNA6 Polyclonal Lapin (ABIN8122417) détecte spécifiquement KPNA6 dans WB et IP. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour KPNA6 anticorps (AA 404-454) (ABIN8122417)

Antigène: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KPNA6 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-KPNA6 anticorps

Épitope: AA 404-454

Fonction: KPNA6 Antibody

Specificité: This antibody detects endogenous levels of KPNA6 at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human KPNA6 AA range: 404-454

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur KPNA6

Antigène: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Autre désignation: KPNA6

Sujet:

Synonyms: Importin subunit alpha-7 (Karyopherin subunit alpha-6)

Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore.The protein encoded byThis gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008],

Gene Name: KPNA6 IPOA7

Protein Name: KPNA6

ID gène: 23633

UniProt: O60684

Pathways: Protein targeting to Nucleus