KRT17 anticorps (AA 300-432)
Aperçu rapide pour KRT17 anticorps (AA 300-432) (ABIN8122459)
Antigène
Voir toutes KRT17 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 300-432
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Fonction
- Cytokeratin 17 mouse mAb
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Specificité
- The antibody can specifically recognize human CK17 protein. In western blotting of Hela and A431 cell lysates, the antibody can label a 46 kDa band corresponding to CK17.
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Purification
- The antibody was purified by protein G affinity chromatography.
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Immunogène
- A synthetic peptide corresponding to the amino acid region 300 - 432 of the human Cytokeratin 17 protein.
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Isotype
- IgG
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Indications d'application
- IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at-20°C. Avoid freeze / thaw cycles.
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- KRT17 (Keratin 17 (KRT17))
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Autre désignation
- Cytokeratin 17
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Sujet
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Synonyms: 39. 1, CK 17, CK-17, CytokeRatin-17, K17, K1C17_HUMAN, KeRatin 17, keRatin 17 epitope S1, keRatin 17 epitope S2, keRatin 17 epitope S4, KeRatin 17, type I, KeRatin, KeRatin type I cytoskeletal 17, keRatin, type i cytoskeletal 17 [version 1], KeRatin-17, KRT17, PC, PC2, PCHC1, type I cytoskeletal 17
Background: CK17 is a cytokeratin with a molecular weight of 46 kDa. It mainly marks the basal cells of stratified epithelium and pseudostratified epithelium. It is also expressed in myoepithelial cells of various glands such as breast, sweat and saliva. It is mainly used for the diagnosis of lung, cervical and oral squamous cell carcinoma. In breast cancer, the positive expression of CK17 is associated with poor prognosis, high tumor grade and axillary lymph node metastasis.
Gene Name: KRT17
Protein Name: Cytokeratin 17
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ID gène
- 3872
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UniProt
- Q04695
Antigène
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