KISS1 anticorps

N° du produit ABIN8122567

Cet anticorps anti-KISS1 Polyclonal Lapin (ABIN8122567) détecte spécifiquement KISS1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour KISS1 anticorps (ABIN8122567)

Antigène: KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KISS1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-KISS1 anticorps

Fonction: KISS1 Antibody

Specificité: KISS1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur KISS1

Antigène: KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

Autre désignation: KISS1

Sujet:

Background: This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by R

Gene Name: KISS1 PP5098

Protein Name: Metastasis-suppressor KiSS-1 (Kisspeptin-1) [Cleaved into: Metastin (Kisspeptin-54)Kisspeptin-14Kisspeptin-13Kisspeptin-10]

ID gène: 3814

UniProt: Q15726

Pathways: Positive Regulation of Peptide Hormone Secretion