LILRB3 anticorps

N° du produit ABIN8122636

Cet anticorps anti-LILRB3 Polyclonal Lapin (ABIN8122636) détecte spécifiquement LILRB3 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Souris et Humain.

Aperçu rapide pour LILRB3 anticorps (ABIN8122636)

Antigène: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Reactivité: Souris, Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LILRB3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-LILRB3 anticorps

Fonction: LIRB3 Antibody

Specificité: LIRB3 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur LILRB3

Antigène: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Autre désignation: LIRB3

Sujet:

Background: LILRB3 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. Leukocyte Immunoglobulin Like Receptor B3 belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: LILRB3 ILT5 LIR3

Protein Name: Leukocyte immunoglobulin-like receptor subfamily B member 3 (LIR-3) (Leukocyte immunoglobulin-like receptor 3) (CD85 antigen-like family member A) (Immunoglobulin-like transcript 5) (ILT-5) (Monocyte inhibitory receptor HL9) (CD antigen CD85a)

ID gène: 11025

UniProt: O75022