Lipin 1 anticorps

N° du produit ABIN8122666

Cet anticorps anti-Lipin 1 Polyclonal Lapin (ABIN8122666) détecte spécifiquement Lipin 1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Lipin 1 anticorps (ABIN8122666)

Antigène: Lipin 1 (LPIN1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lipin 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Lipin 1 anticorps

Fonction: lipin1 (phospho ser889) Antibody

Specificité: This antibody detects endogenous levels of lipin1 ser889 at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human lipin1 ser889

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Lipin 1

Antigène: Lipin 1 (LPIN1)

Autre désignation: lipin1

Sujet:

Synonyms: Phosphatidate phosphatase LPIN1 (EC 3.1.3.4) (Lipin-1)

Background: This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. [provided by RefSeq, May 2012],

Gene Name: LPIN1 KIAA0188

Protein Name: lipin1 ser889

ID gène: 23175

UniProt: Q14693

Pathways: Monocarboxylic Acid Catabolic Process