Lipin 1 anticorps

N° du produit ABIN8122667

Cet anticorps Lapin Polyclonal détecte spécifiquement Lipin 1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Lipin 1 anticorps (ABIN8122667)

Antigène: Lipin 1 (LPIN1)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lipin 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Lipin 1 anticorps

Fonction: LPIN1 Antibody

Specificité: LPIN1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Lipin 1

Antigène: Lipin 1 (LPIN1)

Autre désignation: LPIN1

Sujet:

Background: This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. [provided by RefSeq, May 2012],

Gene Name: LPIN1 KIAA0188

Protein Name: Phosphatidate phosphatase LPIN1 (EC 3.1.3.4) (Lipin-1)

ID gène: 23175

UniProt: Q14693

Pathways: Monocarboxylic Acid Catabolic Process