LRP6 anticorps

N° du produit ABIN8122682

Cet anticorps Lapin Monoclonal détecte spécifiquement LRP6 dans WB, IHC, ELISA, IP et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour LRP6 anticorps (ABIN8122682)

Antigène: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp LRP6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: AB2114

Détail du produit anti-LRP6 anticorps

Fonction: LRP6 Rabbit mAb

Specificité: This antibody detects endogenous levels of LRP6 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: Recombinant protein (or fragment).

Isotype: IgG

Information d'application

Indications d'application: WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur LRP6

Antigène: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Autre désignation: LRP6

Sujet:

Synonyms: Low-density lipoprotein receptor-related protein 6 (LRP-6)

Background: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP-(regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined. [provided by RefSeq, Dec 2009],

Gene Name: LRP6

Protein Name: LRP6

ID gène: 4040

UniProt: O75581

Pathways: Signalisation WNT, Tube Formation