KDM3B anticorps (AA 230-310)

N° du produit ABIN8122715

Cet anticorps Lapin Polyclonal détecte spécifiquement KDM3B dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour KDM3B anticorps (AA 230-310) (ABIN8122715)

Antigène: KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM3B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-KDM3B anticorps

Épitope: AA 230-310

Fonction: KDM3B Antibody

Specificité: KDM3B Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human protein . at AA range: 230-310

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur KDM3B

Antigène: KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

Autre désignation: KDM3B

Sujet:

Background: cofactor:Binds 1 Fe(2+) ion per subunit.,domain:Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.,function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.,miscellaneous:Its gene is located in the 5q region of the genome which is deleted in del(5q) interstitial deletion, a frequent deletion found in myeloid leukemias and myelodysplasias, suggesting that it may be a good candidate for the del(5q) tumor suppressor gene.,similarity:Belongs to the JHDM2 histone demethylase family.,similarity:Contains 1 JmjC domain.,tissue specificity:Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.,

Gene Name: KDM3B C5orf7 JHDM2B JMJD1B KIAA1082

Protein Name: Lysine-specific demethylase 3B (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 2B) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA)

ID gène: 51780

UniProt: Q7LBC6

Pathways: L'effet Warburg