MMP7 anticorps (Cleaved-Tyr95)

N° du produit ABIN8122803

L’anticorps anti-MMP7 Polyclonal Lapin est utilisé pour la détection de MMP7 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour MMP7 anticorps (Cleaved-Tyr95) (ABIN8122803)

Antigène: MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-MMP7 anticorps

Épitope: Cleaved-Tyr95

Fonction: MMP7 (Cleaved-Tyr95) Antibody

Specificité: This antibody detects endogenous levels of Human,Mouse,Rat MMP7 (Cleaved-Tyr95, protein was cleaved amino acid sequence between 94-95 )

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human MMP7 (Cleaved-Tyr95)

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MMP7

Antigène: MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

Autre désignation: MMP7

Sujet:

Synonyms: Matrilysin (EC 3.4.24.23, Matrin, Matrix metalloproteinase-7, MMP-7, Pump-1 protease, Uterine metalloproteinase)

Background: catalytic activity:Cleavage of 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in B chain of insulin. No action on collagen types I, II, IV, V. Cleaves gelatin chain alpha-2(I) > alpha-1(I).,cofactor:Binds 2 calcium ions per subunit.,cofactor:Binds 2 zinc ions per subunit.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.,similarity:Belongs to the peptidase M10A family.,

Gene Name: MMP7 MPSL1 PUMP1

Protein Name: MMP7 (Cleaved-Tyr95)

ID gène: 4316

UniProt: P09237

Pathways: Production of Molecular Mediator of Immune Response