MSH2 anticorps

N° du produit ABIN8122950

L’anticorps anti-MSH2 Monoclonal Souris est utilisé pour la détection de MSH2 dans des échantillons de Humain. Il a été validé pour WB et IHC.

Aperçu rapide pour MSH2 anticorps (ABIN8122950)

Antigène: MSH2 (Mismatch Repair Protein 2 (MSH2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MSH2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: AB1240

Détail du produit anti-MSH2 anticorps

Fonction: MSH2 mouse mAb

Specificité: This antibody detects endogenous levels of MSH2 protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogène: Recombinant protein of the human MSH2 protein.

Isotype: IgG

Information d'application

Indications d'application: IHC, 1:100-1:400 | WB, 1:2000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur MSH2

Antigène: MSH2 (Mismatch Repair Protein 2 (MSH2))

Autre désignation: MSH2

Sujet:

Synonyms: DNA mismatch repair protein Msh2, MutS protein homolog 2, MSH2, hMSH2

Background: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],

Gene Name: MSH2

Protein Name: MutS Protein Homolog 2

ID gène: 3662

UniProt: P43246

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response