MAP3K11 anticorps (pSer281, pThr277)

N° du produit ABIN8123016

L’anticorps anti-MAP3K11 Polyclonal Lapin est utilisé pour la détection de MAP3K11 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour MAP3K11 anticorps (pSer281, pThr277) (ABIN8123016)

Antigène: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K11 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-MAP3K11 anticorps

Épitope: pSer281, pThr277

Fonction: MLK3 (Phospho Thr277+Ser281) Antibody

Specificité: This antibody detects endogenous levels of Human,Mouse,Rat MLK3 (Phospho Thr277+Ser281)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human MLK3 (Phospho Thr277+Ser281)

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MAP3K11

Antigène: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Autre désignation: MLK3

Sujet:

Synonyms: Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinase)

Background: The protein encoded byThis gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008],

Gene Name: MAP3K11 MLK3 PTK1 SPRK

Protein Name: MLK3 (Phospho Thr277+Ser281)

ID gène: 4296

UniProt: Q16584

Pathways: Signalisation MAPK, Interferon-gamma Pathway