NOTCH4 anticorps (Cleaved-Val1467)

N° du produit ABIN8123380

Cet anticorps anti-NOTCH4 Polyclonal Lapin (ABIN8123380) détecte spécifiquement NOTCH4 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Singe.

Aperçu rapide pour NOTCH4 anticorps (Cleaved-Val1467) (ABIN8123380)

Antigène: NOTCH4 (Notch 4 (NOTCH4))

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOTCH4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NOTCH4 anticorps

Épitope: Cleaved-Val1467

Fonction: NOTCH4 (Cleaved-Val1467) Antibody

Specificité: This antibody detects endogenous levels of Human,Monkey NOTCH4 (Cleaved-Val1467, protein was cleaved amino acid sequence between 1466-1467 )

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human NOTCH4 (Cleaved-Val1467)

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur NOTCH4

Antigène: NOTCH4 (Notch 4 (NOTCH4))

Autre désignation: NOTCH4

Sujet:

Synonyms: Neurogenic locus notch homolog protein 4 (Notch 4, hNotch4) [Cleaved into: Notch 4 extracellular truncation, Notch 4 intracellular domain]

Background: notch 4(NOTCH4) Homo sapiens This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which

Gene Name: NOTCH4 INT3

Protein Name: NOTCH4 (Cleaved-Val1467)

ID gène: 4855

UniProt: Q99466

Pathways: Signalisation Notch