ORC2 anticorps (AA 180-260)
Aperçu rapide pour ORC2 anticorps (AA 180-260) (ABIN8123524)
Antigène
Voir toutes ORC2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 180-260
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Fonction
- ORC2 Antibody
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Specificité
- ORC2 Polyclonal Antibody detects endogenous levels of protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from human protein . at AA range: 180-260
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Isotype
- IgG
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Indications d'application
- WB 1:500-2000 ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- ORC2 (Origin Recognition Complex Subunit 2 (ORC2))
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Autre désignation
- ORC2
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Sujet
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Background: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins.The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-me
Gene Name: ORC2 ORC2L
Protein Name: Origin recognition complex subunit 2
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ID gène
- 4999
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UniProt
- Q13416
Antigène
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