PTRF anticorps (AA 90-170)

N° du produit ABIN8123876

Cet anticorps Lapin Polyclonal détecte spécifiquement PTRF dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PTRF anticorps (AA 90-170) (ABIN8123876)

Antigène: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTRF est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PTRF anticorps

Épitope: AA 90-170

Fonction: PTRF Antibody

Specificité: PTRF Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human protein . at AA range: 90-170

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur PTRF

Antigène: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Autre désignation: PTRF

Sujet:

Background: This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrop

Gene Name: PTRF FKSG13

Protein Name: Polymerase I and transcript release factor (Cavin-1)

ID gène: 284119

UniProt: Q6NZI2