S100A1 anticorps (AA 2-92)

N° du produit ABIN8124504

L’anticorps anti-S100A1 Monoclonal Souris est utilisé pour la détection de S100A1 dans des échantillons de Humain, Rat et Souris. Il a été validé pour IHC.

Aperçu rapide pour S100A1 anticorps (AA 2-92) (ABIN8124504)

Antigène: S100A1 (S100 Calcium Binding Protein A1 (S100A1))

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp S100A1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: AB1264

Détail du produit anti-S100A1 anticorps

Épitope: AA 2-92

Fonction: S100 mouse mAb

Specificité: The antibody can specifically recognize human S100B protein, and has a weak reaction with S100A1, but no cross reaction with S100A4 or S100A6.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogène: A synthetic peptide corresponding to the amino acid region 2 - 92 of the human S100 protein.

Isotype: IgG

Information d'application

Indications d'application: IHC, 1:200-1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur S100A1

Antigène: S100A1 (S100 Calcium Binding Protein A1 (S100A1))

Autre désignation: S100

Sujet:

Synonyms: NEF, Protein S100 B, Protein S100-B, S 100 calcium binding protein beta chain, S 100 protein beta chain, S-100 protein beta chain, S-100 protein subunit beta, S100, S100 calcium binding protein beta (neural) , S100 calcium-binding protein B, S100 protein beta chain, S100B, S100B_HUMAN, S100beta

Background: S100 comprises 19 members of Ca2+ binding proteins with low molecular weight between 9 kDa to 13 kDa. The S100 falmily proteins have been implicated to regulate protein phosphorylation, cell proliferation and differentiation in the Ca2+-dependent way. S100B is abundant in glial cells of the central and peripheral nervous system, in melanocytes, chondrocytes, and adipocytes. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. It is a useful marker for the identification of melanoma and various nervous system tumors.

Gene Name: S100B

Protein Name: S100

ID gène: 6285

UniProt: P04271

Pathways: Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins