Sclerostin anticorps (AA 130-210)

N° du produit ABIN8124552

L’anticorps anti-Sclerostin Polyclonal Lapin est utilisé pour la détection de Sclerostin dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour Sclerostin anticorps (AA 130-210) (ABIN8124552)

Antigène: Sclerostin (SOST)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sclerostin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Sclerostin anticorps

Épitope: AA 130-210

Fonction: Sclerostin Antibody

Specificité: Sclerostin Polyclonal Antibody detects endogenous levels of Sclerostin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from Sclerostin . at AA range: 130-210

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Sclerostin

Antigène: Sclerostin (SOST)

Autre désignation: Sclerostin

Sujet:

Synonyms: SOST, Sclerostin

Background: Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008],

Gene Name: SOST

Protein Name: Sclerostin

ID gène: 50964

UniProt: Q9BQB4