TCL1A anticorps (AA 50-114)

N° du produit ABIN8125088

Cet anticorps Souris Monoclonal détecte spécifiquement TCL1A dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TCL1A anticorps (AA 50-114) (ABIN8125088)

Antigène: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TCL1A est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: AB1425

Détail du produit anti-TCL1A anticorps

Épitope: AA 50-114

Fonction: TCL1 Mouse mAb (Ready to Use)

Specificité: The antibody can specifically recognize human TCL1 protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 50 - 114 of the human TCL1 protein.

Isotype: IgG

Information d'application

Indications d'application: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze

Stock: 4 °C

Stockage commentaire: Store at 4°C. Avoid freeze.

Détails sur TCL1A

Antigène: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Autre désignation: TCL1

Sujet:

Synonyms: Anti TCL1A, Lymphoma/leukemia, T-cell, Oncogene TCL-1, Oncogene TCL1, P14 TCL1, P14 TCL1 protein, Protein p14 TCL1, T cell leukemia 1, T cell lymphoma 1, T cell lymphoma 1A, T-cell leukemia/lymphoma 1A, T-cell leukemia/lymphoma protein 1A, TCL 1 protein, TCL1, TCL1 oncogene, TCL1 PEN, Tcl1a, TCL1A, TCL1A_HUMAN

Background: TCL1 belongs to the proto oncogene family. It promotes the nuclear translocation of AKT1 by activating the phosphorylation of AKT1, AKT2 and Akt3, so as to promote cell proliferation and survival and stabilize mitochondrial membrane potential. The encoded protein is involved in embryonic development, T cell carcinogenesis, pre lymphocyte carcinogenesis and B cell carcinogenesis.

Gene Name: TCL1A

Protein Name: TCL1

ID gène: 8115

UniProt: P56279

Pathways: Stem Cell Maintenance