TARDBP anticorps

N° du produit ABIN8125115

Cet anticorps Lapin Monoclonal détecte spécifiquement TARDBP dans WB, IHC, IF, ELISA et IP. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TARDBP anticorps (ABIN8125115)

Antigène: TARDBP (TAR DNA Binding Protein (TARDBP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TARDBP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

Clone: AB1708

Détail du produit anti-TARDBP anticorps

Fonction: TDP43 Rabbit mAb

Specificité: This antibody detects endogenous levels of TDP43 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: Recombinant protein (or fragment).

Isotype: IgG

Information d'application

Indications d'application: WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur TARDBP

Antigène: TARDBP (TAR DNA Binding Protein (TARDBP))

Autre désignation: TDP43

Sujet:

Synonyms: TAR DNA-binding protein 43 (TDP-43)

Background: TAR DNA binding protein (TARDBP) Homo sapiens    HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS) , contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008],

Gene Name: TARDBP TDP43

Protein Name: TDP43

ID gène: 23435

UniProt: Q13148

Pathways: Positive Regulation of Peptide Hormone Secretion