TEK anticorps (pTyr992)

N° du produit ABIN8125139

Cet anticorps Lapin Polyclonal détecte spécifiquement TEK dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour TEK anticorps (pTyr992) (ABIN8125139)

Antigène: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TEK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-TEK anticorps

Épitope: pTyr992

Fonction: Tie-2 (phospho Tyr992) Antibody

Specificité: Phospho-Tie-2 (Y992) Polyclonal Antibody detects endogenous levels of Tie-2 protein only when phosphorylated at Y992.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized phospho-peptide around the phosphorylation site of human Tie-2 (phospho Tyr992)

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TEK

Antigène: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Autre désignation: Tie-2

Sujet:

Synonyms: TEK, TIE2, VMCM, VMCM1, Angiopoietin-1 receptor, Endothelial tyrosine kinase, Tunica interna endothelial cell kinase, Tyrosine kinase with Ig and EGF homology domains-2, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor

Background: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014],

Gene Name: TEK

Protein Name: Angiopoietin-1 receptor

ID gène: 7010

UniProt: Q02763

Pathways: Signalisation RTK, Growth Factor Binding