Thyroperoxidase anticorps (AA 600-700)

N° du produit ABIN8125211

Cet anticorps Souris Monoclonal détecte spécifiquement Thyroperoxidase dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Thyroperoxidase anticorps (AA 600-700) (ABIN8125211)

Antigène: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Thyroperoxidase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: AB1601

Détail du produit anti-Thyroperoxidase anticorps

Épitope: AA 600-700

Fonction: Thyroid Peroxidase (TPO) mouse mAb

Specificité: This antibody detects endogenous levels of TPO protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 600 - 700 of the human Thyroid Peroxidase protein.

Isotype: IgG

Information d'application

Indications d'application: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur Thyroperoxidase

Antigène: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Autre désignation: Thyroid Peroxidase

Sujet:

Synonyms: Thyroid peroxidase,TPO,

Background: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]

Gene Name: TPO

Protein Name: Thyroid Peroxidase (TPO)

ID gène: 3662

UniProt: P07202

Pathways: Thyroid Hormone Synthesis