TICAM1 anticorps (AA 663-712)

N° du produit ABIN8125243

Cet anticorps anti-TICAM1 Polyclonal Lapin (ABIN8125243) détecte spécifiquement TICAM1 dans WB, IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TICAM1 anticorps (AA 663-712) (ABIN8125243)

Antigène: TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TICAM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-TICAM1 anticorps

Épitope: AA 663-712

Fonction: TRIF Antibody

Specificité: TRIF Polyclonal Antibody detects endogenous levels of TRIF

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from TRIF at AA range: 663-712

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-200 ELISA 1:10000-20000. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TICAM1

Antigène: TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))

Autre désignation: TRIF

Sujet:

Synonyms: TIR domain-containing adapter molecule 1 (TICAM-1, Proline-rich, vinculin and TIR domain-containing protein B, Putative NF-kappa-B-activating protein 502H, Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta, TIR domain-containing adapter protein inducing IFN-beta)

Background: This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. [provided by RefSeq, Jan 2012],

Gene Name: TICAM1

Protein Name: TRIF

ID gène: 148022

UniProt: Q8IUC6

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades