Topoisomerase II alpha anticorps (AA 1400-1531)

N° du produit ABIN8125247

Cet anticorps Souris Monoclonal détecte spécifiquement Topoisomerase II alpha dans IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Topoisomerase II alpha anticorps (AA 1400-1531) (ABIN8125247)

Antigène: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Topoisomerase II alpha est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: AB1403

Détail du produit anti-Topoisomerase II alpha anticorps

Épitope: AA 1400-1531

Fonction: Topoisomerase IIα mouse mAb

Specificité: The antibody can specifically recognize human Topoisomerase IIα protein.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogène: A synthetic peptide corresponding to the amino acid region 1400 - 1531 of the human Topoisomerase IIalpha protein.

Isotype: IgG

Information d'application

Indications d'application: IHC, 1:200-1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur Topoisomerase II alpha

Antigène: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Autre désignation: Topoisomerase IIalpha

Sujet:

Synonyms: alpha isozyme, ATP hydrolyzing DNA topoisomerase II alfa, DNA gyrase, DNA topoisomerase (ATP hydrolyzing) , DNA topoisomerase 2 alpha, DNA topoisomerase 2-alpha, DNA topoisomerase II 170 kD, DNA topoisomerase II alpha isozyme, DNA topoisomerase II, DNA Topoisomerase2, TOP 2A, TOP2, TOP2A, TOP2A_HUMAN, Topoisomerase DNA II alpha 170 kDa, TP2A

Background: Topoisomerase IIα (Topo IIα) is a nuclear protein with a molecular weight of 170 kDa. It belongs to the topoisomerase family and is expressed in proliferating cells. The main function is to maintain the spatial conformation of DNA and ensure its function. It is mainly used for the study of drug resistance.

Gene Name: TOP2A

Protein Name: Topoisomerase IIα

ID gène: 7153

UniProt: P11388

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases