Vitamin D Receptor anticorps (AA 150-250)

N° du produit ABIN8125720

Cet anticorps anti-Vitamin D Receptor Monoclonal Souris (Clone AB2465) (ABIN8125720) détecte spécifiquement Vitamin D Receptor dans WB, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Vitamin D Receptor anticorps (AA 150-250) (ABIN8125720)

Antigène: Vitamin D Receptor (VDR)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Vitamin D Receptor est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: AB2465

Détail du produit anti-Vitamin D Receptor anticorps

Épitope: AA 150-250

Fonction: Vitamin D Receptor mouse mAb

Specificité: This antibody detects endogenous levels of Vitamin D Receptor protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 150 - 250 of the human Vitamin D Receptor protein.

Isotype: IgG

Information d'application

Indications d'application: WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur Vitamin D Receptor

Antigène: Vitamin D Receptor (VDR)

Autre désignation: Vitamin D Receptor

Classe de substances: Chemical

Sujet:

Synonyms: Vitamin D3 receptor, VDR, 1, 25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, NR1I1

Background: vitamin D (1, 25-dihydroxyvitamin D3) receptor (VDR) Homo sapiens This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011],

Gene Name: VDR

Protein Name: Vitamin D Receptor

ID gène: 7421

UniProt: P11473

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway