BMI1 anticorps

N° du produit ABIN781174

Cet anticorps anti-BMI1 est un anticorps Souris Monoclonal détectant BMI1 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour BMI1 anticorps (ABIN781174)

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BMI1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-BMI1 anticorps

Specificité: Nucleus

Purification: Protein G-Sepharose affinity purified

Immunogène: Synthetic peptide from the N-terminal region of human Bmi1, conjugated to KLH.

Isotype: IgG

Information d'application

Indications d'application: Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 50µg/50µl

Buffer: 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur BMI1

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Autre désignation: Bmi1

Sujet: The Bmi1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells. Bmi1 extends the replicative life span of human fibroblasts by suppressing the p16-dependent senescence pathway. Bmi1 plays a central role in the inheritance of stemness, and its forced expression promotes HSC self-renewal. These findings highlight the importance of epigenetic regulation in HSC self-renewal and identify PcG genes as potential targets for therapeutic HSC manipulation.

Poids moléculaire: 37kDa

NCBI Accession: NM_005180

Pathways: Cycle Cellulaire, Autophagy