MED1 anticorps

N° du produit ABIN781182

L’anticorps anti-MED1 Monoclonal produit chez le Souris a été validé pour WB et ELISA. Il convient pour la détection de MED1 dans des échantillons provenant de Humain. }

Aperçu rapide pour MED1 anticorps (ABIN781182)

Antigène: MED1 (Mediator Complex Subunit 1 (MED1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MED1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MED1 anticorps

Specificité: Nucleus

Purification: Protein G-Sepharose affinity purified

Immunogène: Recombinant fragment of Human MED1 (C-terminus).

Isotype: IgG

Information d'application

Indications d'application: Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 50µg/50µl

Buffer: 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur MED1

Antigène: MED1 (Mediator Complex Subunit 1 (MED1))

Autre désignation: MED1

Sujet: MED1 work with coactivators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. It also regulates p53 dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize.

Poids moléculaire: 45kDa

NCBI Accession: NM_004774

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha