PKM2 anticorps
Aperçu rapide pour PKM2 anticorps (ABIN781224)
Antigène
Voir toutes PKM2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Protein G-Sepharose affinity purified.
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Immunogène
- Recombinant fragment of Human PKM2 (N-terminus).
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Isotype
- IgG
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Indications d'application
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 50µg/50µl
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Buffer
- 0.02% Sodium Azide, 50% glycerol, 1% BSA, PBS, PH7.4.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- PKM2 (Pyruvate Kinase M2 (PKM2))
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Autre désignation
- PKM2
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Sujet
- PKM2 (pyruvate kinase, muscle) catalyzes the production of phosphoenol pyruvate from pyruvate and ATP. PKM2 has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. It has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.
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Poids moléculaire
- 45kDa
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NCBI Accession
- NM_182471
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Pathways
- L'effet Warburg
Antigène
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