GRP78 anticorps

N° du produit ABIN781236

L’anticorps anti-GRP78 Monoclonal Souris est utilisé pour la détection de GRP78 dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour GRP78 anticorps (ABIN781236)

Antigène: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GRP78 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GRP78 anticorps

Specificité: E ndoplasmic reticulum

Purification: Protein G-Sepharose affinity purified.

Immunogène: Recombinant fragment of Human HSPA5 (C-terminus).

Information d'application

Indications d'application: Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 50µg/50µl

Buffer: 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur GRP78

Antigène: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Autre désignation: HSPA5

Sujet: The 78 kDa glucose regulated protein/BiP (GRP78) belongs to the family of ~70 kDa heat shock proteins (HSP 70). GRP78 is a resident protein of the endoplasmic reticulum (ER) and may associate transiently with a variety of newly synthesized secretory and membrane proteins or permanently with mutant or defective proteins that are incorrectly folded, thus preventing their export from the ER lumen. GRP78 is a highly conserved protein that is essential for cell viability.

Poids moléculaire: 48kDa

NCBI Accession: NM_005354

Pathways: Thyroid Hormone Synthesis, ER-Nucleus Signaling