CR1L anticorps
Aperçu rapide pour CR1L anticorps (ABIN781721)
Antigène
Voir toutes CR1L AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody detects Crry. The antigen is found on numerous cells in blood and various tissues.
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Réactivité croisée (Details)
- Species reactivity (tested):Rat
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Purification
- Affinity chromatography
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Immunogène
- Erythrocytes from a C3 mutated rat
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Reconstitution
- Reconstitute by adding 0.5 mL distilled water.
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Buffer
- Stock solution contains 0.4 mg/mL IgG, phosphate buffered saline pH 7.2 (PBS), 5 mg/mL bovine serum albumin (BSA) as a stabilizer and 0.09 % sodium azide as a preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.
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- CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))
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Autre désignation
- CR1L / CRRY
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Sujet
- Crry is a cofactor for complement factor I. Crry seems to act as a costimulatory factor for T-cells and is expressed on different tissues, particularly also on thymocytes and non-lymphoid cells in the thymus. Crry may play an important role in the early embryonic development by maintaining fetomaternal tolerance. Two forms of Crry exist, containing six or seven extracellular short consensus repeats (SCRs), respectively, plus a transmembrane and a cytoplasmic domain. The molecular weights of the native glycoproteins are approximately 55 and 65 kDa, respectively.Synonyms: Antigen 5I2, Complement component receptor 1-like protein, Complement regulatory protein Crry
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ID gène
- 54243
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NCBI Accession
- NP_001005265
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UniProt
- Q63135
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Pathways
- Système du Complément
Antigène
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