CR1L anticorps

N° du produit ABIN781721

L’anticorps anti-CR1L Monoclonal Souris est utilisé pour la détection de CR1L dans des échantillons de Rat. Il a été validé pour IHC (fro) et FACS.

Aperçu rapide pour CR1L anticorps (ABIN781721)

Antigène: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CR1L est non-conjugé

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)

Clone: 512

Détail du produit anti-CR1L anticorps

Specificité: This antibody detects Crry. The antigen is found on numerous cells in blood and various tissues.

Réactivité croisée (Details): Species reactivity (tested):Rat

Purification: Affinity chromatography

Immunogène: Erythrocytes from a C3 mutated rat

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Reconstitute by adding 0.5 mL distilled water.

Buffer: Stock solution contains 0.4 mg/mL IgG, phosphate buffered saline pH 7.2 (PBS), 5 mg/mL bovine serum albumin (BSA) as a stabilizer and 0.09 % sodium azide as a preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

Détails sur CR1L

Antigène: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Autre désignation: CR1L / CRRY

Sujet: Crry is a cofactor for complement factor I. Crry seems to act as a costimulatory factor for T-cells and is expressed on different tissues, particularly also on thymocytes and non-lymphoid cells in the thymus. Crry may play an important role in the early embryonic development by maintaining fetomaternal tolerance. Two forms of Crry exist, containing six or seven extracellular short consensus repeats (SCRs), respectively, plus a transmembrane and a cytoplasmic domain. The molecular weights of the native glycoproteins are approximately 55 and 65 kDa, respectively.Synonyms: Antigen 5I2, Complement component receptor 1-like protein, Complement regulatory protein Crry

ID gène: 54243

NCBI Accession: NP_001005265

UniProt: Q63135

Pathways: Système du Complément