Ferritin anticorps

N° du produit ABIN781724

Détail du produit anti-Ferritin anticorps

Antigène: Ferritin (FE)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ferritin est non-conjugé

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Affinity chromatography

Immunogène: Ferritin from human spleen and liver

Clone: MAb 44

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Reconstitute by adding 0.5 mL distilled water.

Buffer: Stock solution contains 0.4 mg/mL IgG, phosphate buffered saline pH 7.2 (PBS), 10 mg/mL bovine serum albumin (BSA) as a stabilizer and 0.01 % thimerosal as a preservative

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

Détails sur Ferritin

Antigène: Ferritin (FE)

Autre désignation: Ferritin (FE Produits)

Synonymes: anticorps 1HCH, anticorps BEST:LD36673, anticorps CG2216, anticorps Dmel\\CG2216, anticorps FER1, anticorps FER1HCH, anticorps Fer-L, anticorps Fer1, anticorps Fer1HC, anticorps FerHCH, anticorps HCH, anticorps T21, anticorps T9, anticorps fer1, anticorps fer1hch, anticorps l(3)00451, anticorps l(3)j10B4, anticorps SFerH-1, anticorps SOF-35, anticorps SOF-5L, anticorps NV13011, anticorps ACP1, anticorps F8A5.24, anticorps F8A5_24, anticorps Ferritin 1 heavy chain homologue, anticorps ferritin light chain, anticorps ferritin, anticorps chromosome 26 open reading frame, human C10orf131, anticorps hyaluronan and proteoglycan link protein 2, anticorps NAD(P)-linked oxidoreductase superfamily protein, anticorps Fer1HCH, anticorps H-1, anticorps YPDSF_1340, anticorps ftnA, anticorps Ft, anticorps C26H10orf131, anticorps HAPLN2, anticorps AT1G60730

Sujet: Ferritin consists of a mineral core of hydrated ferric oxide, and a multi-subunit protein shell which englobes the former and assures its solubility in an aqueous environment. It is mainly localized intracellularly in cells of the reticuloendothelial system as well as in liver, spleen and bone marrow. Elevated serum levels are found in patients with iron overload and in other diseases such as pernicious anaemia, chronic inflammations such as rheumatoid arthritis (RA), hepatocellular carcinoma and Hodgkin's disease. Ferritin consists of two components, the apoferritin and the iron core (FeIII - hydroxyphosphate-micelle). The apoferritin is a globular protein built up of 24 subunits that can bind up to 4500 iron atoms. Other non-ferrous metal ions such as Al or Be can also bind to ferritin, which acts partly as a metal ion detoxicant.Synonyms: FTH, FTL, Ferritin H subunit, Ferritin L subunit

Pathways: Transition Metal Ion Homeostasis