TSG101 anticorps
Aperçu rapide pour TSG101 anticorps (ABIN781822)
Antigène
Voir toutes TSG101 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody reacts to TSG101.
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Purification
- Protein A chromatography
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Immunogène
- TSG101 antibody was raised against recombinant protein
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Isotype
- IgG2a
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0,5 mg/mL
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Buffer
- PBS, pH 7.2
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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Autre désignation
- TSG101
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Sujet
- The tumor susceptibility gene 101 (TSG101) was first discovered in a screen for potential tumor suppressors. Altered transcripts of this gene have been detected in sporadic breast carcinomas and other malignancies. In mice the gene has been shown to be essential for growth, proliferation and survival of mammary epithelial cells. TSG101 is also a component of the ESCRt-1 complex, a regulator of the vesicular trafficking process. In addition it is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies and is involved the budding of many viruses.Synonyms: ESCRT-I complex subunit TSG101, Tumor susceptibility gene 101 protein
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ID gène
- 7251
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NCBI Accession
- NP_006283
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UniProt
- Q99816
Antigène
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