C3AR1 anticorps (AA 63-8)

N° du produit ABIN782447

Détail du produit anti-C3AR1 anticorps

Antigène: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Épitope: AA 63-8

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp C3AR1 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This rat C3a receptor antibody detects a recombinant peptide corresponding to amino acids 161-321 of the large extracellular loop structure, which shares 34 % homology with mouse and human. Deduced amino acid sequences of human/rat C3aR is 58.5 % and 90.7 % with rat/mouse.

Purification: Affinity chromatography on Protein G

Immunogène: RBL-2H3 transfectants expressing rat C3aR Donor: BALB/c Fusion Partner: X63-Ag8.653

Clone: 74

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN3) as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur C3AR1

Antigène: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Abstract: C3AR1 Produits

Synonymes: anticorps C3AR, anticorps C3a-R, anticorps c3ar1, anticorps AZ3B, anticorps HNFAG09, anticorps C3a anaphylatoxin chemotactic receptor, anticorps complement C3a receptor 1, anticorps complement component 3a receptor 1, anticorps c3ar1, anticorps C3AR1, anticorps C3ar1

Sujet: C3aR binds to anaphylotoxin C3a which, among other things, is involved in mast cell degranulation and recruitment of immune cells to the site of inflammation. Activation of the complement cascade produces various fragments, including C3a and C5a. C3aR is characterized by seven transmembrane domains including a large extracellular loop which is coupled to a Gi protein. C3aR expression is detected on glial cells, neurons and cells belonging to the mononuclear phagocyte system. C3aR expression was shown to moderately increase after LPS stimulation.Synonyms: AZ3B, C3AR, C3AR1, C3R1, C3a anaphylatoxin chemotactic receptor, C3a-R, HNFAG09

ID gène: 84007

NCBI Accession: NP_114449

UniProt: O55197

Pathways: Système du Complément