CR1L anticorps (Biotin)
Aperçu rapide pour CR1L anticorps (Biotin) (ABIN782449)
Antigène
Voir toutes CR1L AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Anti-Rat Crry monoclonal antibody (Clone: 5I2) is a rat-specific membrane complement regulator that can inhibit both antibody-induced classical pathway and alternative pathway complement activation. Crry plays a more dominant role than DAF in regulating the alternative pathway of complement and in preventing spontaneous complement damage of rat erythrocytes, whereas DAF and Crry are both expressed and are equally effective in preventing antibody-induced runaway complement activation on rat erythrocytes.
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Immunogène
- Erythrocytes from a C3 mutated rat
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0,1 mg/mL
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Buffer
- PBS containing 0.02 % sodium azide (NaN3) and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))
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Autre désignation
- CR1L / CRRY
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Sujet
- Synonyms: Antigen 5I2, Complement component receptor 1-like protein, Complement regulatory protein Crry
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ID gène
- 54243
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NCBI Accession
- NP_001005265
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UniProt
- Q63135
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Pathways
- Système du Complément
Antigène
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