ESRP2 anticorps (C-Term)

N° du produit ABIN783407

Détail du produit anti-ESRP2 anticorps

Antigène: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ESRP2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects ESRP2 / RBM35B at C-term. RBM35B antibody is predicted to not cross-react with other RBM35/ESRP family members. At least three isoforms of RBM35B are known to exist, this antibody will detect all three.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide near the carboxy terminus of human RBM35B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur ESRP2

Antigène: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Autre désignation: ESRP2 / RBM35B (ESRP2 Produits)

Synonymes: anticorps RBM35B, anticorps 9530027K23Rik, anticorps Rbm35b, anticorps RGD1310855, anticorps cb404, anticorps fa07a06, anticorps rbm35b, anticorps sb:cb404, anticorps zgc:77254, anticorps epithelial splicing regulatory protein 2, anticorps microRNA 6773, anticorps ESRP2, anticorps Esrp2, anticorps MIR6773, anticorps esrp2

Sujet: RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing programme induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.Synonyms: Epithelial splicing regulatory protein 2, RNA-binding motif protein 35B, RNA-binding protein 35B

ID gène: 80004

NCBI Accession: NP_079215

UniProt: Q9H6T0