PRR5 anticorps (C-Term)
Aperçu rapide pour PRR5 anticorps (C-Term) (ABIN783442)
Antigène
Voir toutes PRR5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- This antibody detects PRR5 at C-term. PRR5 antibody is predicted to not cross-react with other Protor protein family members.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 20 amino acid peptide near the carboxy terminus of human PRR5
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- PRR5 (Proline Rich 5 (Renal) (PRR5))
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Autre désignation
- PRR5
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Sujet
- Proline-rich protein 5 (PRR5), also known as Protor-1, is a 388 amino acid protein in Protor family, is thought to act as a tumor suppressor in breast and colorectal tumorigenesis. PRR5 is widely expressed and possesses two RICTOR interaction sites and a C-terminal Proline rich region. It promotes Rapamycin complex 2 (mTORC2) activity. There are four isoforms of PRR5 that are produced as a result of alternative splicing events and these isoforms play an important role in the modulation of platelet-derived growth factor signaling and in the regulation of PDGFR-β expression.Synonyms: PROTOR1, Proline-rich protein 5, Protein observed with Rictor-1, Protor-1
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ID gène
- 55615
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NCBI Accession
- NP_001017528
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UniProt
- P85299
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Pathways
- Signalisation PI3K-Akt
Antigène
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