RASSF10 anticorps (N-Term)

N° du produit ABIN783486

Détail du produit anti-RASSF10 anticorps

Antigène: RASSF10 (Ras Association (RalGDS/AF-6) Domain Family (N-Terminal) Member 10 (RASSF10))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASSF10 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects RASSF10 at N-term. RASSF10 antibody will not cross-react with other RAS association domain-containing family members.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide near the amino terminus of human RASSF10

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-RASSF10 (ABIN783486)

Sherwood, Manbodh, Sheppard, Chalmers: "RASSF7 is a member of a new family of RAS association domain-containing proteins and is required for completing mitosis." dans: Molecular biology of the cell, Vol. 19, Issue 4, pp. 1772-82, (2008) (PubMed).

Détails sur RASSF10

Antigène: RASSF10 (Ras Association (RalGDS/AF-6) Domain Family (N-Terminal) Member 10 (RASSF10))

Autre désignation: RASSF10 (RASSF10 Produits)

Synonymes: anticorps 4632411J06Rik, anticorps Ras association domain family member 10, anticorps Ras association (RalGDS/AF-6) domain family (N-terminal) member 10, anticorps RASSF10, anticorps Rassf10

Sujet: RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer. These proteins consist of RASSF7-10 and are structurally distinct from RASSF1-6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains. While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas. In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic associated with worst progression-free survival and overall survival.Synonyms: Ras association domain-containing protein 10

ID gène: 644943

NCBI Accession: NP_001073990

UniProt: A6NK89