RASSF10 anticorps (N-Term)

N° du produit ABIN6991539

Détail du produit anti-RASSF10 anticorps

Antigène: RASSF10 (Ras Association (RalGDS/AF-6) Domain Family (N-Terminal) Member 10 (RASSF10))

Épitope: AA 50-100, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASSF10 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: RASSF10 antibody will not cross-react with other RAS association domain-containing family members.

Purification: RASSF10 Antibody is affinity chromatography purified via peptide column.

Immunogène: RASSF10 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human RASSF10. The immunogen is located within amino acids 50 - 100 of RASSF10.

Isotype: IgG

Information d'application

Indications d'application: RASSF10 antibody can be used for detection of RASSF10 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: RASSF10 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: RASSF10 antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur RASSF10

Antigène: RASSF10 (Ras Association (RalGDS/AF-6) Domain Family (N-Terminal) Member 10 (RASSF10))

Autre désignation: RASSF10 (RASSF10 Produits)

Synonymes: anticorps 4632411J06Rik, anticorps Ras association domain family member 10, anticorps Ras association (RalGDS/AF-6) domain family (N-terminal) member 10, anticorps RASSF10, anticorps Rassf10

Sujet: RASSF10 Antibody: RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer. These proteins consist of RASSF7-10 and are structurally distinct from RASSF1-6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains. While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas. In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic associated with worst progression-free survival and overall survival.

ID gène: 644943

NCBI Accession: NP_001073990

UniProt: A6NK89