AP3S1 anticorps (Center)

N° du produit ABIN783504

Détail du produit anti-AP3S1 anticorps

Antigène: AP3S1 (Adaptor-Related Protein Complex 3, sigma 1 Subunit (AP3S1))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AP3S1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: At least three isoforms of AP3S1 are known to exist, this antibody will detect the two larger isoforms. AP3S1 antibody is predicted to not cross-react with other AP3 protein family members.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: Raised against a 19 amino acid peptide near the center of human AP3S1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur AP3S1

Antigène: AP3S1 (Adaptor-Related Protein Complex 3, sigma 1 Subunit (AP3S1))

Autre désignation: AP3 Complex Subunit sigma-1 (AP3S1 Produits)

Synonymes: anticorps CLAPS3, anticorps Sigma3A, anticorps [s]3A, anticorps adaptor related protein complex 3 sigma 1 subunit, anticorps adaptor-related protein complex 3, sigma 1 subunit, anticorps adaptor related protein complex 3 sigma 1 subunit S homeolog, anticorps AP3S1, anticorps Ap3s1, anticorps ap3s1.S

Sujet: AP3S1 belongs to the adaptor complexes 3 (AP3) small subunit family which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3 is an heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). AP3S1 Interacts with AGAP1 and may play an important role in carcinoma.Synonyms: AP-3 complex sigma-3A subunit, AP3S1, Adapter-related protein complex 3 sigma-1 subunit, CLAPS3, Clathrin-associated assembly/adapter protein, Sigma 3A Adaptin, Sigma-3A-adaptin, Sigma-adaptin 3a, small 3

ID gène: 1176

NCBI Accession: NP_001275

UniProt: Q92572