CCDC141 anticorps (N-Term)

N° du produit ABIN783520

Cet anticorps Lapin Polyclonal détecte spécifiquement CCDC141 dans WB et EIA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour CCDC141 anticorps (N-Term) (ABIN783520)

Antigène: CCDC141 (Coiled-Coil Domain Containing 141 (CCDC141))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCDC141 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-CCDC141 anticorps

Épitope: N-Term

Specificité: This antibody detects CCDC141 at N-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid peptide near the amino terminus of human CCDC141

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur CCDC141

Antigène: CCDC141 (Coiled-Coil Domain Containing 141 (CCDC141))

Autre désignation: CCDC141

Sujet: Coiled-coil domain-containing protein 141 (CCDC141), also known as CAMDI, is a recently identified disrupted in schizophrenia 1 (DISC1)-binding protein that also associates with myosin II. CCDC141 preferentially associates with phosphomyosin II and causes an accumulation of phosphomyosin II at the centrosome in a DISC1-dependent manner. Knockdown of CCDC141 expression by RNAi led to severely impaired radial migration with disoriented chromosomes, suggesting that CCDC141 is required for radial migration through DISC1 and myosin II-mediated centrosome positioning during neuronal development. At least four isoforms of CCDC141 are known to exist.Synonyms: Coiled-coil domain-containing protein 141

ID gène: 285025

NCBI Accession: NP_775919

UniProt: Q6ZP82